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ICSI · KANAA FERTILITY

ICSI (Intracytoplasmic Sperm Injection) Treatment

When sperm-related factors make fertilisation difficult, ICSI gives your eggs the best possible chance. A single, healthy sperm is carefully selected and injected directly into each mature egg by our expert embryologists — as part of your IVF cycle. Available at our KK Nagar and Mylapore clinics in Chennai.

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4
Key Steps
1
IVF Cycle
On request
Starting Price

ICSI (Intracytoplasmic Sperm Injection) at Kanaa Fertility is an advanced IVF technique used when sperm-related factors make natural fertilisation difficult — a single, healthy sperm is injected directly into each mature egg to help fertilisation happen. Two clinics in KK Nagar & Mylapore, with in-person & online consultations.

WHAT IS ICSI

ICSI — A More Precise Way to Fertilise the Egg

One of the most advanced fertilisation techniques available, used within an IVF cycle when help is needed to bring egg and sperm together.

Image placeholder — medical illustration needed (sperm injected into egg, under magnification). Clinic to confirm style or provide licensed/original imagery.

ICSI and IVF are essentially the same procedure — eggs and sperm are collected the same way. The only real difference is how fertilisation happens.

In a standard IVF cycle, sperm and eggs are placed together in a dish, and fertilisation happens naturally, on its own. With ICSI, our embryologist selects a single, healthy-looking sperm and injects it directly into the centre of a mature egg, using a fine glass needle under a high-powered microscope.

This extra step is especially helpful when sperm count, movement, or shape make it harder for fertilisation to happen on its own — or when a previous IVF cycle did not result in fertilisation.

A precision technique

Fertilisation is guided carefully in the lab, not left to chance.

Ideal for male-factor infertility

Even a very low sperm count or weak movement can still be used.

Performed by expert embryologists

Every sperm and egg is handled carefully, under high magnification.

SPERM SELECTION

How Is Sperm Selected for ICSI?

Sperm selection is where ICSI's precision really matters. Our embryologist examines the sample under a high-magnification microscope, assessing each sperm's shape, structure, and movement before choosing the healthiest-looking one for each egg.

If a sample has very few sperm, or none in the ejaculate, sperm can sometimes be retrieved directly through a minor surgical procedure.

Sample quality

Whether fresh or frozen sperm is being used.

Motility & morphology

Movement and shape are assessed carefully under the microscope.

Best candidate selection

The single healthiest-looking sperm is chosen for each mature egg.

Surgically retrieved sperm, if needed

For very low counts, sperm can sometimes be collected directly.

Every step is explained to you as we go — you will always know where your treatment stands.

Image placeholder — real lab / embryology imagery needed from the clinic. Do not use generic stock photography.
WHO IS IT FOR

Who Is ICSI Recommended For?

ICSI is not for everyone — your Kanaa specialist recommends it only after a proper fertility evaluation. It is often considered when:

Very Low Sperm Count

When there are very few sperm available, ICSI gives each one the best chance to fertilise an egg.

Abnormal Sperm Shape or Movement

When a high number of sperm are irregularly shaped or slow-moving.

After a Previous Vasectomy

Sperm retrieved surgically can still be used successfully with ICSI.

Lower-Quality Frozen Sperm

When frozen sperm is not of the best quality, ICSI can still achieve fertilisation.

Difficulty with Erection or Ejaculation

When these make natural conception difficult, sperm can be collected and used via ICSI.

Absence of Sperm in the Ejaculate

Whether due to a blockage or how sperm is produced, sperm can often still be retrieved for ICSI.

Fertility Preservation Before Cancer Treatment

For patients who froze sperm before treatments like chemotherapy, ICSI can help use that sample later.

Severely Reduced Sperm Motility

Including cases where sperm show very little or no movement at all.

Not sure if it is right for you? A consultation is the clearest way to find out.

THE PROCESS

The ICSI Process at Kanaa Fertility

A clear, step-by-step path through one IVF cycle — every protocol personalised to you.

1
Ovarian Stimulation

Medicines are given to help your ovaries produce multiple mature eggs.

2
Egg Retrieval

Once eggs are mature, they are collected in a short procedure under sedation.

3
Sperm Collection & Preparation

A fresh or frozen sample is collected and prepared in the lab on the same day.

4
ICSI (Sperm Injection)

Using a specialised instrument called a micromanipulator, the embryologist steadies the mature egg with a holding pipette, then carefully picks up a single sperm with a fine injection pipette and injects it directly into the egg’s cytoplasm.

5
Fertilisation Check

Embryologists check for signs of successful fertilisation, usually within 16–18 hours of injection.

6
Embryo Culture

Fertilised eggs are monitored in the lab. Within 5–6 days, a healthy fertilised egg should divide into a blastocyst.

7
Embryo Transfer

Transfer usually happens on day 5 or 6 after retrieval — or transfer may be delayed, with embryos frozen through a process called vitrification for future use.

SUCCESS RATES

ICSI Success Rates

Success with ICSI depends on egg quality, sperm quality, age, and how embryos develop in the lab — so no honest clinic can promise a single number for everyone. What we can promise is realistic, transparent guidance based on your own situation, and a clear conversation about your chances before you begin.

FACTORS

Factors That Affect Success

Understanding what influences ICSI success helps you and your specialist plan realistically. The main factors:

Age

Egg quality and quantity naturally decline with age, especially after 35.

Egg Quality

Healthier, more mature eggs are more likely to fertilise and develop well.

Sperm Quality

Even with ICSI, healthier sperm generally means better outcomes.

Embryo Quality

How well the fertilised egg develops in the lab matters for transfer.

Uterine Environment

A receptive uterine lining is essential for implantation.

Lifestyle

Weight, smoking, alcohol and stress all play a role — and many are within your control.

Your specialist reviews all of these together to give you an honest, personalised picture.

WHY KANAA

Why Choose Kanaa Fertility?

Fertility care that combines medical expertise, careful monitoring, and compassionate support.

Experienced Fertility Specialists

A skilled team specialised in reproductive medicine.

Careful, Close Monitoring

Scans and dose adjustments guided at every step.

Personalised Protocols

Your treatment designed around your body and diagnosis.

Compassionate, Patient-First Care

Support at every step of your journey.

Two Convenient Locations in Chennai

KK Nagar & Mylapore, with flexible scheduling.

TREATMENT OPTIONS

ICSI vs IVF vs IUI — What is Right for You?

These treatments are steps on the same path — the right one depends on your diagnosis. Your specialist recommends whichever gives you the best realistic chance.

IUI

IUI (Intrauterine Insemination)

Prepared sperm is placed directly into the uterus at the right moment. Often combined with ovulation induction when sperm needs a little help getting there.

IVF

IVF (In Vitro Fertilisation)

Eggs and sperm are combined in the lab and left to fertilise naturally, then a healthy embryo is placed in the uterus.

ICSI

ICSI

A single sperm is injected directly into each egg. Recommended when sperm count, movement, or shape make natural fertilisation difficult, or after a previous IVF fertilisation attempt did not succeed.

Many couples move to ICSI when sperm-related factors need extra help — we will always explain why it is the right step for you.

RISKS & SIDE EFFECTS

Risks & Side Effects

Common and usually mild

  • Mild bloating after egg retrieval
  • Cramping or spotting for a day or two
  • Tiredness from stimulation medicines
  • Mild bruising or soreness at injection sites

Less common, worth knowing

  • Ovarian Hyperstimulation Syndrome (OHSS) — An over-response to stimulation medicines. Careful monitoring keeps the risk low.
  • Egg or Embryo Sensitivity — A very small number of eggs may not survive the injection process.
  • Fertilisation Failure — Rarely, even with ICSI, some eggs may not fertilise.
  • Multiple Pregnancy — If more than one embryo is transferred, there is a higher chance of twins.

This is exactly why we monitor so closely — your scans and lab updates let us adjust as we go. Please call us any time you are unsure, or if anything does not feel right.

YOUR QUESTIONS

Questions to Ask Your Doctor

Bring these to your consultation — we welcome open, honest conversations.

  • Why is ICSI the right option for us, rather than standard IVF?
  • What is likely causing our sperm-related difficulty?
  • How many eggs and sperm do we need for a good chance of success?
  • What is our realistic chance of success per cycle?
  • What happens if fertilisation does not happen?
  • How many embryos will you transfer, and what happens to the rest?
  • Are there lifestyle changes that would help?
FAQ

Frequently Asked Questions

What is the difference between IVF and ICSI?
ICSI and IVF are essentially the same process — eggs and sperm are collected the same way. The only difference is how fertilisation happens: in IVF, sperm and egg are left together to fertilise naturally; in ICSI, a single sperm is injected directly into the egg.
When is ICSI recommended?
ICSI is recommended in several situations — including very low sperm count, abnormal sperm shape or movement, previous vasectomy, poor-quality frozen sperm, or when sperm needs to be surgically retrieved. Your specialist will confirm if it is right for you.
Is ICSI painful?
The injection itself happens in the lab on the egg, not on you — so you will not feel it. Any discomfort comes from the egg retrieval procedure, which is done under sedation.
How is sperm collected for ICSI?
Most often by a fresh sample on the day of egg retrieval. If needed, sperm can also be retrieved surgically or a previously frozen sample can be used.
Can ICSI be done with frozen sperm?
Yes — frozen sperm can be used for ICSI, and success rates are generally comparable to fresh samples.
How many sperm are needed for ICSI?
Very few — sometimes just one healthy sperm per egg — which is why ICSI can help even in cases of extremely low sperm count.
What is the success rate of ICSI?
Success depends on age, egg quality, sperm quality, and embryo development — your specialist will walk you through a realistic estimate for your specific situation during your consultation.
What is the disadvantage of ICSI?
Like any fertility procedure, ICSI does not guarantee fertilisation or pregnancy, and there is a very small risk of egg damage during the injection process. Your specialist will talk you through this in detail.
How many hours after ICSI does fertilisation occur?
Fertilisation is usually checked within 16 to 18 hours of the injection.
How much does ICSI cost in Chennai?
Cost varies based on your individual protocol and any additional procedures needed. Please contact us for a personalised estimate.
How many embryos are transferred after ICSI?
This is decided with your specialist based on embryo quality, your age, and your medical history.
Does ICSI increase the risk of birth defects?
This is a common and important question — please raise it directly with your specialist, who can walk you through the current evidence.
How long does one ICSI cycle take?
From the start of stimulation medicines to embryo transfer, one cycle typically takes a few weeks.

Ready to Take Your First Step?

Book a consultation at Kanaa Fertility, Chennai — KK Nagar & Mylapore. Honest, personalised guidance at every step.